UniProt Accession

 GLCT_BACSU;  O31691;  O06710

Genbank Protein ID

 Y11193;  AL009126

Genbank Nucleotide ID

 CAA72077.1;  CAB13261.2

Protein Name

 PtsGHI operon antiterminator

Protein Synonyms/Alias

 

Gene Name

 glcT

Gene Synonyms/Alias

 ykwA; OrderedLocusNames=BSU13880

Created Date

 3-June-2014

Organism

 Bacillus subtilis (strain 168)

NCBI Taxa ID

 224308

Phosphorylation

Reference

 [1]Regulation of the Bacillus subtilis GlcT antiterminator protein by components of the phosphotransferase system.
 Bachem S,Stülke J
 J. Bacteriol. 1998, Oct;180(20):5319-26. [PMID:9765562]

Functional Description From UniProt

 FUNCTION: Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence

Sequence Annotation From UniProt

 MOD_RES 104 104 Phosphohistidine; by EII-Glc
 MOD_RES 163 163 Phosphohistidine; by EII-Glc (Probable)
 MOD_RES 211 211 Phosphohistidine; by HPr (Probable)

Key Word From UniProt

 3D-structure; Activator; Completeproteome; Phosphoprotein; Referenceproteome; Repeat; RNA-binding; Transcription; Transcriptionregulation

Protein Sequence

  GO:0003723   F:RNA binding IEA:UniProtKB-KW
  GO:0045893   P:positive regulation of transcription, DNA-templated IEA:InterPro
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW

  IPR004341   CAT_RNA-bd_dom.
  IPR011608   PRD.
  IPR001550   Transcrpt_antitermin_CS.

  PF03123   CAT_RBD.
  PF00874   PRD.

  SM01061   CAT_RBD.

  PS00654   PRD_1.
  PS51372   PRD_2.