※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RIO-type serine/threonine-protein kinase Rio1
Protein Synonyms/Alias
 AfRio1
Gene Name
 rio1
Gene Synonyms/Alias
 AF_1804
Created Date
 3-June-2014
Organism
 Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
NCBI Taxa ID
 224325
Phosphorylation
Position
Peptide
Code
Type
References
108 RFDMRRISPKEKVFI S LTP;HTP [1,2],UniProt
Reference
 [1]Crystal structure of A. fulgidus Rio2 defines a new family of serine protein kinases.
 LaRonde-LeBlanc N,Wlodawer A
 Structure 2004, Sep;12(9):1585-94. [PMID:15341724]
 [2]Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life.
 Aivaliotis M,Macek B,Gnad F,Reichelt P,Mann M,Oesterhelt D
 PLoS ONE 2009;4(3):e4777. [PMID:19274099]
Functional Description From UniProt
 FUNCTION: Autophosphorylation of the rio1 protein is not necessary for maintenance of kinase activity. Prefers ATP over GTP. The yeast ortholog is involved in ribosome biogenesis
Sequence Annotation From UniProt
 MOD_RES 108 108 Phosphoserine; by autocatalysis
Key Word From UniProt
 3D-structure; ATP-binding; Completeproteome; Directproteinsequencing; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Phosphoprotein; Referenceproteome; Serine/threonine-proteinkinase; Transferase
Protein Sequence
 MKDLKKIESY LDKLRIKEKD GEERKIYAEV LDGRTLKTLY KLSAKGYITA MGGVISTGKE 60
 ANVFYADGVF DGKPVAMAVK IYRIETSEFD KMDEYLYGDE RFDMRRISPK EKVFIWTEKE 120
 FRNLERAKEA GVSVPQPYTY MKNVLLMEFI GEDELPAPTL VELGRELKEL DVEGIFNDVV 180
 ENVKRLYQEA ELVHADLSEY NIMYIDKVYF IDMGQAVTLR HPMAESYLER DVRNIIRFFS 240
 KYGVKADFEE MLKEVKGE 258
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0046872   F:metal ion binding IEA:UniProtKB-KW
  GO:0004674   F:protein serine/threonine kinase activity IEA:UniProtKB-KW
  IPR011009   Kinase-like_dom.
  IPR000719   Prot_kinase_dom.
  IPR018934   RIO-like_kinase.
  IPR000687   RIO_kinase.
  IPR018935   RIO_kinase_CS.
  PF01163   RIO1.
  SM00090   RIO.
  PS50011   PROTEIN_KINASE_DOM.
  PS01245   RIO1.