※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein translocase subunit SecY
Protein Synonyms/Alias
 
Gene Name
 secY
Gene Synonyms/Alias
 HP_1300
Created Date
 3-June-2014
Organism
 Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
NCBI Taxa ID
 85962
Phosphorylation
Position
Peptide
Code
Type
References
113 RYLTILITLIQAVSV T HTP [1]
121 LIQAVSVSVGLRSIS S HTP [1]
109 MQIVRYLTILITLIQ T HTP [1]
119 ITLIQAVSVSVGLRS S HTP [1]
Reference
 [1]Phosphoproteome analysis of the pathogenic bacterium Helicobacter pylori reveals over-representation of tyrosine phosphorylation and multiply phosphorylated proteins.
 Ge R,Sun X,Xiao C,Yin X,Shan W,Chen Z,He QY
 Proteomics 2011, Apr;11(8):1449-61. [PMID:21360674]
Functional Description From UniProt
 FUNCTION: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Sequence Annotation From UniProt
 TRANSMEM 9 29 Helical; (Potential)
 TRANSMEM 61 81 Helical; (Potential)
 TRANSMEM 104 124 Helical; (Potential)
 TRANSMEM 141 161 Helical; (Potential)
 TRANSMEM 173 193 Helical; (Potential)
 TRANSMEM 203 223 Helical; (Potential)
 TRANSMEM 257 277 Helical; (Potential)
 TRANSMEM 300 320 Helical; (Potential)
 TRANSMEM 355 375 Helical; (Potential)
 TRANSMEM 377 397 Helical; (Potential)
Key Word From UniProt
 Cellinnermembrane; Cellmembrane; Completeproteome; Membrane; Proteintransport; Referenceproteome; Translocation; Transmembrane; Transmembranehelix; Transport
Protein Sequence
 MNKAIASKIL ITLGFLFLYR VLAYIPIPGV DLAAIKAFFD SNSNNALGLF NMFSGNAVSR 60
 LSIISLGIMP YITSSIIMEL LSATFPNLAK MKKERDGMQK YMQIVRYLTI LITLIQAVSV 120
 SVGLRSISGG ANGAIMIDMQ VFMIVSAFSM LTGTMLLMWI GEQITQRGVG NGISLIIFAG 180
 IVSGIPSAIS GTFNLVNTGV INILMLIGIV LIVLATIFAI IYVELAERRI PISYARKVVM 240
 QNQNKRIMNY IPIKLNLSGV IPPIFASALL VFPSTILQQA TSNKTLQAVA DFLSPQGYAY 300
 NILMFLLIIF FAYFYSSIVF NSKDIADNLR RNGGYIPGLR PGEGTSSFLN SVASKLTLWG 360
 SLYLALISTV PWILVKAMGV PFYFGGTAVL IVVQVAIDTM KKIEAQIYMS KYKTLSAVGF 420
  GO:0016021   C:integral component of membrane IEA:UniProtKB-KW
  GO:0005622   C:intracellular IEA:GOC
  GO:0005886   C:plasma membrane IEA:UniProtKB-SubCell
  GO:0065002   P:intracellular protein transmembrane transport IEA:UniProtKB-HAMAP
  GO:0006605   P:protein targeting IEA:UniProtKB-HAMAP
  GO:0043952   P:protein transport by the Sec complex IEA:UniProtKB-HAMAP
  IPR026593   SecY.
  IPR002208   SecY/SEC61-alpha.
  IPR023201   SecY_su_dom.
  PF00344   SecY.
  PS00755   SECY_1.
  PS00756   SECY_2.