| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Queuine tRNA-ribosyltransferase |
Protein Synonyms/Alias | |
Gene Name | tgt |
Gene Synonyms/Alias | HP_0281 |
Created Date | 3-June-2014 |
Organism | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
NCBI Taxa ID | 85962 |
Phosphorylation | Position | Peptide | Code | Type | References | | 315 | CKRYSKAYLHHLFRA | Y | HTP | [1] | | 312 | CYACKRYSKAYLHHL | S | HTP | [1] | |
Reference | [1]Phosphoproteome analysis of the pathogenic bacterium Helicobacter pylori reveals over-representation of tyrosine phosphorylation and multiply phosphorylated proteins. Ge R,Sun X,Xiao C,Yin X,Shan W,Chen Z,He QY Proteomics 2011, Apr;11(8):1449-61. [ PMID:21360674] |
Functional Description From UniProt | FUNCTION: Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) |
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| Completeproteome; Glycosyltransferase; Metal-binding; Queuosinebiosynthesis; Referenceproteome; Transferase; tRNAprocessing; Zinc |
Protein Sequence | MDFQLQATDN NARAGLLNLA HSQVATPVFM PVGTQGCIKS LDATDAQEIL GAKLILANTY 60
HMYLRPGEKV VEELGGLHRF AQFYGSFLTD SGGFQAFSLS DNVKLQEDGI VFKSHIDGSK 120
HLFTPAKVLD IQYSLNSDIM MVLDDLVGLP APLKRLEESI KRSAKWANMS LEYHKEKNRP 180
SNNLFAIIQG GTHLKMRSLS VGLTHEGFDG YAIGGLAVGE SADEMLETIA HTAPLLPKDK 240
PRYLMGVGTP ENILDAISLG VDMFDCVMPT RNARNATLFT HSGKISIKNA PYKLDNTPIE 300
ENCACYACKR YSKAYLHHLF RAKELTYARL ASLHNLHFYL ELVKNARNAI LEKRFLSFKK 360
EFLEKYNSRS H 371 |
| GO:0046872 F:metal ion binding IEA:UniProtKB-KW GO:0008479 F:queuine tRNA-ribosyltransferase activity IEA:UniProtKB-HAMAP GO:0008616 P:queuosine biosynthetic process IEA:UniProtKB-HAMAP |
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