Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Signal recognition particle 54 kDa protein |
Protein Synonyms/Alias | SRP54 |
Gene Name | srp54 |
Gene Synonyms/Alias | ffh; OrderedLocusNames=Saci_1310 |
Created Date | 3-June-2014 |
Organism | Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) |
NCBI Taxa ID | 330779 |
Phosphorylation | Position | Peptide | Code | Type | References | 419 | VKELLKQYQMTNNLL | Y | HTP | [1] | 422 | LLKQYQMTNNLLKMV | T | HTP | [1] | |
Reference | [1]Archaeal signal transduction: impact of protein phosphatase deletions on cell size, motility, and energy metabolism in Sulfolobus acidocaldarius. Reimann J,Esser D,Orell A,Amman F,Pham TK,Noirel J,Lindås AC,Bernander R,Wright PC,Siebers B,Albers SV Mol. Cell Proteomics 2013, Dec;12(12):3908-23. [ PMID:24078887] |
Functional Description From UniProt | FUNCTION: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (By similarity) |
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| Completeproteome; Cytoplasm; GTP-binding; Nucleotide-binding; Ribonucleoprotein; RNA-binding; Signalrecognitionparticle |
Protein Sequence | MLDGLRDAVR KFLGSSDYEK AVNEFIKELQ IILIKADVNV RLVKDLTDRI KKRITEEKPP 60 SAIEKREWFI SIVYDELSRL FGGDKEPEVM PKKLPYIIML VGVQGSGKTT TSGKLALFYK 120 KKGYKVGLVA ADIYRPAAYE QLIQIGQQIN IPVYGEPGNK NPIEIATNGL EKFLKEKMNI 180 VIIDTAGRHG YGEEASLLEE MKSMYDKIHP DEVILVIDAS IGQKAYDLAS RFHQASPIGS 240 LIVSKMDGTA KGGGALSAVI ATGAQIKFIG TGEKLDELEV FNPRRFVSRL LGLGDIESII 300 EKIKSVEDYE NLEKRMEDVI SGKTKLTLRD IYKQLIALRK MGPLGKIFQM LPGAGILSQV 360 PEEQLKLGEE KIRTFMAIMN SMTYKELDNP SIIDKARMRR IAKGAGVTVE EVKELLKQYQ 420 MTNNLLKMVK RRKGLAKLFG GSNQ 444 |
| GO:0005786 C:signal recognition particle, endoplasmic reticulum targeting IEA:UniProtKB-KW GO:0008312 F:7S RNA binding IEA:UniProtKB-HAMAP GO:0005525 F:GTP binding IEA:UniProtKB-HAMAP GO:0003924 F:GTPase activity IEA:UniProtKB-HAMAP GO:0006614 P:SRP-dependent cotranslational protein targeting to membrane IEA:InterPro |
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