| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | N5-carboxyaminoimidazole ribonucleotide synthase |
Protein Synonyms/Alias | N5-CAIR synthase |
Gene Name | purK |
Gene Synonyms/Alias | SSO1065 |
Created Date | 3-June-2014 |
Organism | Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) |
NCBI Taxa ID | 273057 |
Phosphorylation | Position | Peptide | Code | Type | References | | 321 | VLKYGKVYWYSKSEV | Y | HTP | [1] | | 317 | IPVEVLKYGKVYWYS | Y | HTP | [1] | | 323 | KYGKVYWYSKSEVRK | Y | HTP | [1] | | 324 | YGKVYWYSKSEVRKR | S | HTP | [1] | |
Reference | [1]Change of carbon source causes dramatic effects in the phospho-proteome of the archaeon Sulfolobus solfataricus. Esser D,Pham TK,Reimann J,Albers SV,Siebers B,Wright PC J. Proteome Res. 2012, Oct, 5;11(10):4823-33. [ PMID:22639831] |
Functional Description From UniProt | FUNCTION: Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) (By similarity) |
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| ATP-binding; Completeproteome; Ligase; Nucleotide-binding; Purinebiosynthesis; Referenceproteome |
Protein Sequence | MFSVLDWKPK IGILGGGQLG WMIVLEGRKY PFTFYVLEND KNAPACRIAD RCFSPQDYKE 60
FVDSSDVITF EFEHVYEKAL EYAEYSGKLL PRLNSVELKR ERYKEKLFYR QHNLPTPRFY 120
VAEDGEEALK ILREEFNNVG VIKESKGGYD GKGQYFIFND VEKYQFLREK KEKMVVEEYV 180
KFDFEASIII ARDKRGVFIS YPPTYNYNEK GILVYNYGPY NNQNIVEIAR RLSEELDYVG 240
IMGVEVFVVN GKVLINEFAP RVHNTGHYTL DGALISQFEQ HLRAIIGMEL GPSTILSPSG 300
MVNILGTDKI PVEVLKYGKV YWYSKSEVRK RRKMGHVNVV GNNLEEVKQK IDKIMQLIYT 360
NGLDL 365 |
| GO:0034028 F:5-(carboxyamino)imidazole ribonucleotide synthase activity IEA:UniProtKB-EC GO:0005524 F:ATP binding IEA:UniProtKB-KW GO:0046872 F:metal ion binding IEA:InterPro GO:0004638 F:phosphoribosylaminoimidazole carboxylase activity IEA:InterPro GO:0006189 P:'de novo' IMP biosynthetic process IEA:UniProtKB-UniPathway |
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