| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex |
Protein Synonyms/Alias | BCKADH E2 |
Gene Name | bkdC |
Gene Synonyms/Alias | pdhC; OrderedLocusNames=Rv2495c |
Created Date | 3-June-2014 |
Organism | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
NCBI Taxa ID | 83332 |
Phosphorylation | Position | Peptide | Code | Type | References | | 55 | KAEVEIPSPYAGRIV | S | HTP | [1] | |
Reference | [1]Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Prisic S,Dankwa S,Schwartz D,Chou MF,Locasale JW,Kang CM,Bemis G,Church GM,Steen H,Husson RN Proc. Natl. Acad. Sci. U.S.A. 2010, Apr, 20;107(16):7521-6. [ PMID:20368441] |
Functional Description From UniProt | FUNCTION: Component of the branched-chain alpha-ketoacid dehydrogenase (BCKADH) complex, that catalyzes the overall conversion of branched-chain alpha-ketoacids to acyl-CoA and CO(2) |
| MOD_RES 48 48 N6-lipoyllysine (By similarity) |
| 3D-structure; Acyltransferase; Completeproteome; Lipoyl; Referenceproteome; Transferase |
Protein Sequence | MSGEDSIRSF PVPDLGEGLQ EVTVTCWSVA VGDDVEINQT LCSVETAKAE VEIPSPYAGR 60
IVELGGAEGD VLKVGAELVR IDTGPTAVAQ PNGEGAVPTL VGYGADTAIE TSRRTSRPLA 120
APVVRKLAKE LAVDLAALQR GSGAGGVITR ADVLAAARGG VGAGPDVRPV HGVHARMAEK 180
MTLSHKEIPT AKASVEVICA ELLRLRDRFV SAAPEITPFA LTLRLLVIAL KHNVILNSTW 240
VDSGEGPQVH VHRGVHLGFG AATERGLLVP VVTDAQDKNT RELASRVAEL ITGAREGTLT 300
PAELRGSTFT VSNFGALGVD DGVPVINHPE AAILGLGAIK PRPVVVGGEV VARPTMTLTC 360
VFDHRVVDGA QVAQFMCELR DLIESPETAL LDL 393 |
| GO:0005618 C:cell wall IDA:MTBBASE GO:0005886 C:plasma membrane IDA:MTBBASE GO:0043754 F:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity IEA:UniProtKB-EC |
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