※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleoside diphosphate kinase
Protein Synonyms/Alias
 NDK;  NDP kinase
Gene Name
 ndk
Gene Synonyms/Alias
 SMWW4_v1c37220
Created Date
 3-June-2014
Organism
 Serratia marcescens WW4
NCBI Taxa ID
 435998
Phosphorylation
Position
Peptide
Code
Type
References
124 HGSDSVESAQREIAY S HTP [1]
119 TANAVHGSDSVESAQ S HTP [1]
121 NAVHGSDSVESAQRE S HTP [1]
112 ADYADSFTANAVHGS T HTP [1]
Reference
 [1]Proteomic identification of novel secreted antibacterial toxins of the Serratia marcescens type VI secretion system.
 Fritsch MJ,Trunk K,Diniz JA,Guo M,Trost M,Coulthurst SJ
 Mol. Cell Proteomics 2013, Oct;12(10):2735-49. [PMID:23842002]
Functional Description From UniProt
 FUNCTION: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 ATP-binding; Completeproteome; Cytoplasm; Endonuclease; Hydrolase; Kinase; Magnesium; Metal-binding; Nuclease; Nucleotidemetabolism; Nucleotide-binding; Phosphoprotein; Transferase
Protein Sequence
 MTVERTFSIV KPNAVANNDI GAIYARFERA GFKIIAAKML RLTREQAEGF YAEHKGRPFF 60
 DGLVEFMTSG PIMVQVLESE NAVQRNRDIM GATNPDNALA GTLRADYADS FTANAVHGSD 120
 SVESAQREIA YFFNESEICA R 141
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-HAMAP
  GO:0004519   F:endonuclease activity IEA:UniProtKB-KW
  GO:0046872   F:metal ion binding IEA:UniProtKB-KW
  GO:0004550   F:nucleoside diphosphate kinase activity IEA:UniProtKB-HAMAP
  GO:0006241   P:CTP biosynthetic process IEA:UniProtKB-HAMAP
  GO:0006183   P:GTP biosynthetic process IEA:UniProtKB-HAMAP
  GO:0006228   P:UTP biosynthetic process IEA:UniProtKB-HAMAP
  IPR001564   Nucleoside_diP_kinase.
  IPR023005   Nucleoside_diP_kinase_AS.
  PF00334   NDK.
  SM00562   NDK.
  PS00469   NDP_KINASES.
  PR01243   NUCDPKINASE.