UniProt Accession

 K7VUQ6_LACLC;  K7VUQ6

Genbank Protein ID

 CP003157

Genbank Nucleotide ID

 AFW91229.1

Protein Name

 Methionine aminopeptidase

Protein Synonyms/Alias

 MAP;  MetAP

Gene Name

 pepM

Gene Synonyms/Alias

 map; ORFNames=uc509_0616

Created Date

 3-June-2014

Organism

 Lactococcus lactis subsp. cremoris UC509.9

NCBI Taxa ID

 1111678

Phosphorylation

Reference

 [1]Discovery of a new genetic variant of methionine aminopeptidase from Streptococci with possible post-translational modifications: biochemical and structural characterization.
 Arya T,Kishor C,Saddanapu V,Reddi R,Addlagatta A
 PLoS ONE 2013;8(10):e75207. [PMID:24124477]

Functional Description From UniProt

 FUNCTION: Removes the N-terminal methionine from nascent proteins The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Aminopeptidase; Completeproteome; Hydrolase; Metal-binding; Protease.

Protein Sequence

  GO:0046872   F:metal ion binding IEA:UniProtKB-HAMAP
  GO:0070006   F:metalloaminopeptidase activity IEA:UniProtKB-HAMAP
  GO:0070084   P:protein initiator methionine removal IEA:UniProtKB-HAMAP

  IPR000994   Pept_M24_structural-domain.
  IPR002467   Pept_M24A_MAP1.

  PF00557   Peptidase_M24.