UniProt Accession

 B1XQV0_SYNP2;  B1XQV0

Genbank Protein ID

 CP000954

Genbank Nucleotide ID

 ACB00881.1

Protein Name

 CRISPR-associated endonuclease Cas1

Protein Synonyms/Alias

 

Gene Name

 cas1

Gene Synonyms/Alias

 SYNPCC7002_D0019

Created Date

 3-June-2014

Organism

 Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)

NCBI Taxa ID

 32049

Phosphorylation

Reference

 [1]Global phosphoproteomic analysis reveals diverse functions of serine/threonine/tyrosine phosphorylation in the model cyanobacterium Synechococcus sp. strain PCC 7002.
 Yang MK,Qiao ZX,Zhang WY,Xiong Q,Zhang J,Li T,Ge F,Zhao JD
 J. Proteome Res. 2013, Apr, 5;12(4):1909-23. [PMID:23461524]

Functional Description From UniProt

 FUNCTION: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Antiviraldefense; Completeproteome; Endonuclease; Hydrolase; Magnesium; Manganese; Metal-binding; Nuclease; Plasmid

Protein Sequence

  GO:0004519   F:endonuclease activity IEA:UniProtKB-HAMAP
  GO:0046872   F:metal ion binding IEA:UniProtKB-HAMAP
  GO:0051607   P:defense response to virus IEA:UniProtKB-HAMAP
  GO:0043571   P:maintenance of CRISPR repeat elements IEA:UniProtKB-HAMAP

  IPR002729   CRISPR-assoc_Cas1.
  IPR023843   CRISPR-assoc_Cas1_cyanobact.

  PF01867   Cas_Cas1.