※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA mismatch repair protein MutL
Protein Synonyms/Alias
 
Gene Name
 mutL
Gene Synonyms/Alias
 SYNPCC7002_A0649
Created Date
 3-June-2014
Organism
 Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
NCBI Taxa ID
 32049
Phosphorylation
Position
Peptide
Code
Type
References
547 ALEETSLYRFFRRHW Y HTP [1]
545 YLALEETSLYRFFRR S HTP [1]
538 CPHGRPIYLALEETS Y HTP [1]
544 IYLALEETSLYRFFR T HTP [1]
Reference
 [1]Global phosphoproteomic analysis reveals diverse functions of serine/threonine/tyrosine phosphorylation in the model cyanobacterium Synechococcus sp. strain PCC 7002.
 Yang MK,Qiao ZX,Zhang WY,Xiong Q,Zhang J,Li T,Ge F,Zhao JD
 J. Proteome Res. 2013, Apr, 5;12(4):1909-23. [PMID:23461524]
Functional Description From UniProt
 FUNCTION: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Completeproteome; DNAdamage; DNArepair.
Protein Sequence
 MANIKQLPND VIQLIAAGEV IDSLAAVVRE LAENAIDAGA TRINIDIQPQ RWQIRVVDNG 60
 QGMDLEDLQQ CALPHRTSKI GDRQDLAHIK SLGFRGEALH SIAQVAKLTI ASCQDGQPGY 120
 QLTVQQNHVS EPLLKPMAVG TMVTVTDIFQ NFPVRRHALP AIAQQLKTAQ QMIYHLALGQ 180
 PQITWQVNQN NQPWFVISAG KNAQEILPQL LRSISIQDLI FQRYQATDFL TENNSDYATS 240
 YLEVVLGLPD RCHRHQADWL KLAINGRIVK FSALEQAIMK GFSRTLPRDR HPICFVHLHV 300
 PPEHIDWNRH PAKSEIYLQH QTLWQEIIPQ AIAKGLSFSE ANLPRLENQR VLSLIQAAEK 360
 KENYSIEPPS EHSTTSASNP HKKVLKVIGQ ARNTYIITEH PDGIWLVEQH IADERAIYED 420
 LCKNWQLISP IQPVLLNDLS PKQIEQLTDQ LGLDLEIFGE NVWRVNTIPR ALQGHSDLEA 480
 ALLELSRGGD LEAAQVAIAC RTAVRNGTPL DFPTMQTIID RWQQCENPST CPHGRPIYLA 540
 LEETSLYRFF RRHWVLGKSH GITEK 565
  GO:0005524   F:ATP binding IEA:InterPro
  GO:0030983   F:mismatched DNA binding IEA:InterPro
  GO:0006298   P:mismatch repair IEA:UniProtKB-HAMAP
  IPR013507   DNA_mismatch_repair_C.
  IPR014762   DNA_mismatch_repair_CS.
  IPR002099   DNA_mismatch_repair_fam.
  IPR020667   DNA_mismatch_repair_MutL.
  IPR003594   HATPase_ATP-bd.
  IPR014790   MutL_C.
  IPR020568   Ribosomal_S5_D2-typ_fold.
  IPR014721   Ribosomal_S5_D2-typ_fold_subgr.
  PF01119   DNA_mis_repair.
  PF08676   MutL_C.
  SM00387   HATPase_c.
  SM00853   MutL_C.
  PS00058   DNA_MISMATCH_REPAIR_1.