Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation factor 2 |
Protein Synonyms/Alias | EF-2 |
Gene Name | fusA |
Gene Synonyms/Alias | OE_4729R |
Created Date | 3-June-2014 |
Organism | Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) |
NCBI Taxa ID | 478009 |
Phosphorylation | Position | Peptide | Code | Type | References | 388 | FESIDHISEPVITKS | S | HTP | [1] | 393 | HISEPVITKSIEAQN | T | HTP | [1] | 634 | DVRIDVPSEHMGAAS | S | HTP | [1] | 383 | EEMTPFESIDHISEP | S | HTP | [1] | 379 | TVSNEEMTPFESIDH | T | HTP | [1] | |
Reference | [1]Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life. Aivaliotis M,Macek B,Gnad F,Reichelt P,Mann M,Oesterhelt D PLoS ONE 2009;4(3):e4777. [ PMID:19274099] |
Functional Description From UniProt | FUNCTION: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) |
| MOD_RES 596 596 Diphthamide (By similarity) |
| Completeproteome; Cytoplasm; Elongationfactor; GTP-binding; Nucleotide-binding; Proteinbiosynthesis |
Protein Sequence | MGRRKKIVEQ CERLMDNPEQ IRNIAIAAHV DHGKTTLTDN LLAGAGMISE DTAGQQLAMD 60 TEEDEQERGI TIDAANVSMT HEYEGDDHLI NLIDTPGHVD FGGDVTRAMR AVDGALVVVD 120 AVEGAMPQTE TVVRQALREG VKPTLFINKV DRLISELQEG PEEMQERLLS VIGDVNELIR 180 GMTEEKDDIE DWTVSVEDGT VAFGSALYKW GVSMPSMQRT GMDFGDIIDL ERSDKREELH 240 EQTPLADVVL DMVAEHFPNP IDAQPRRIPT VWRGDADSEI AESMRLVDED GEVVLMVTDI 300 GVDPHAGEIA AGRVFSGTLE KGQELYVSGT AGKNRVQSVG IYMGGEREEV DEVPAGNIAA 360 VTGLKDAIAG STVSNEEMTP FESIDHISEP VITKSIEAQN MDDLPKLIET LRQVSKEDPT 420 ISIEINEDTG EHLISGQGEL HLEVQTQRIE RNQGIPVTTG EPIVVYRETP TSDSQEVEGV 480 SPNRHNKFYI TVEQLSDDVL EEIRLGEVSM DMPEQERREV LQEAGMDKET SQDVENIIGR 540 NIFIDDTKGI QHLNETMELV VDGLTDSLED GPLAAEPVEG ALIRLHDARL HEDAIHRGPA 600 QVIPATRDAV HRALIDADIR LLEPIQDVRI DVPSEHMGAA SGEVQGRRGR VDDMYQEGDL 660 MVVEGIAPVD EMIGFSSDIR SATEGRASWN TENAGFRVMA DNLQREIIME IRERKGMKTE 720 LPESITHF 728 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0005525 F:GTP binding IEA:UniProtKB-HAMAP GO:0003924 F:GTPase activity IEA:InterPro GO:0003746 F:translation elongation factor activity IEA:UniProtKB-HAMAP |
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