UniProt Accession

 LUXU_VIBCB;  A7MVC1;  Q9ZBB6

Genbank Protein ID

 CP000789

Genbank Nucleotide ID

 ABU71911.1

Protein Name

 Phosphorelay protein LuxU

Protein Synonyms/Alias

 

Gene Name

 luxU

Gene Synonyms/Alias

 VIBHAR_02958

Created Date

 3-June-2014

Organism

 Vibrio campbellii (strain ATCC BAA-1116 / BB120)

NCBI Taxa ID

 338187

Phosphorylation

Reference

 [1]Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing.
 Ulrich DL,Kojetin D,Bassler BL,Cavanagh J,Loria JP
 J. Mol. Biol. 2005, Mar, 25;347(2):297-307. [PMID:15740742]

Functional Description From UniProt

 FUNCTION: Phosphorelay protein which receives sensory signals from LuxN and LuxP and transmits them to LuxO, at low cell density LuxN and LuxP transfer a phosphoryl group to LuxU on His-58 and this phosphoryl group is further transferred to LuxO. At high cell density, as LuxU could function to establish an equilibrium between the aspartyl-phosphate of LuxN and the aspartyl-phosphate of LuxO, LuxU transfers phosphate from LuxO to LuxN (and probably LuxP) and finally phosphate is drained from the system

Sequence Annotation From UniProt

 MOD_RES 58 58 Phosphohistidine (By similarity)

Key Word From UniProt

 Completeproteome; Phosphoprotein; Two-componentregulatorysystem.

Protein Sequence

  GO:0004871   F:signal transducer activity IEA:InterPro
  GO:0000160   P:phosphorelay signal transduction system IEA:UniProtKB-KW

  IPR008207   Sig_transdc_His_kin_Hpt_dom.

  PF01627   Hpt.

  SM00073   HPT.

  PS50894   HPT.