| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase |
Protein Synonyms/Alias | |
Gene Name | purP |
Gene Synonyms/Alias | SSO0239 |
Created Date | 3-June-2014 |
Organism | Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) |
NCBI Taxa ID | 273057 |
Phosphorylation | Position | Peptide | Code | Type | References | | 219 | LRRLPFEYMKELKIN | Y | HTP | [1] | |
Reference | [1]Change of carbon source causes dramatic effects in the phospho-proteome of the archaeon Sulfolobus solfataricus. Esser D,Pham TK,Reimann J,Albers SV,Siebers B,Wright PC J. Proteome Res. 2012, Oct, 5;11(10):4823-33. [ PMID:22639831] |
Functional Description From UniProt | FUNCTION: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates (By similarity) |
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| ATP-binding; Completeproteome; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Referenceproteome |
Protein Sequence | MIIATIGSHS ALQILHGAKK EGFQTMVITD NKRENFYKNF SFIDNIYAYA SLDEAVSIIN 60
GIKDYGILIP HGSLVEYLGK ERVDKIETKI FGNKKIFEWE ADQKKKMELL RKSNIKIPEI 120
FERPEDVDRL VIVKLNGAKG GKGYFLARNK SEVKEGIQKL IESKMIRDEN EVIIQEYVVG 180
VPMYFQFFYS DIINRTEIFG IDIRYETNID GLRRLPFEYM KELKINPTFV VVGNIPAVAR 240
ESLLPVALEY ANNFVRTTKE LVPPGMIGPF CLESIITDNS DIVVFEFSGR IVAGTNLYVN 300
GSPYSWLYWD EPMSIGRRIA REIRVANEKD KLSLVVS 337 |
| GO:0005524 F:ATP binding IEA:UniProtKB-HAMAP GO:0016879 F:ligase activity, forming carbon-nitrogen bonds IEA:UniProtKB-HAMAP GO:0000287 F:magnesium ion binding IEA:UniProtKB-HAMAP GO:0030145 F:manganese ion binding IEA:UniProtKB-HAMAP GO:0006189 P:'de novo' IMP biosynthetic process IEA:UniProtKB-UniPathway |
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